|
Other information of Interest
Medical Spas
Tubal Reverse Surgery
Bad Credit
Refinancing
Long Term Care Insurance
Looking
for MySpace?
| |
MCPIP | Heartdisease |
Heartattack
|
Newly Discovered
Protein Could Hold Key to Preventing Heartdisease |
Heartattacks
|
|
|
|
WASHINGTON: A newly
discovered gene known as MCPIP could provide scientists
with the key to developing treatments for preventing
inflammation that can cause heart disease,
according to University of Central Florida researchers.
A research team led by Pappachan Kolattukudy, dean of the
UCF Burnett College of Biomedical Sciences, found that the
levels of MCPIP increased in mice as their blood
vessels became inflamed and heart disease began to
develop. The formation of MCPIP leads to the death
of healthy cells, so treatments that block that formation
could prove effective for heart disease.
The researchers are trying to discover the molecular
changes that occur as heart disease develops.
Better understanding those molecular changes would help
with the development of drugs that can either prevent or
treat heart disease.
The laboratory mice developed heart disease in a way
similar to how it forms in humans, which suggests that the
findings could hold promise for treating human heart
disease. However, more research is needed to evaluate
whether the same results found in mice could be expected
in humans.
|
The UCF research team
already has found that MCPIP is elevated in human hearts
suffering ischemic heart failure.
MCPIP is formed when an often-studied protein called MCP-1
binds to receptors. The MCP-1 protein helps to attract
white blood cells known as monocytes to infected and
injured areas of the body. The monocytes then attack
bacteria and help the body fight diseases.
But that process also produces several known and unknown
proteins. The researchers focused on MCPIP, one of the
previously unknown proteins, because they discovered links
between it and the deaths of healthy cells adjacent to the
infected ones.
This finding could lead to advances in treating other
inflammatory diseases such as arthritis and some forms of
cancer.
###
Heartattack - Cause, Signs
and Treatment
|
Continue your
search for Heart disease and Heart attack
|
|
|
|
Source:
Cardiovascular research is one of four main specialties at the Burnett College
of Biomedical Sciences, which laid the foundation for the recently approved
medical college at UCF. Kolattukudy began his research at Ohio State
University before he moved to UCF in 2003.
- - - -
CONTACTS: Chad Binette, UCF News & Information, 407-823-6312, cbinette@mail.ucf.edu
Pappachan Kolattukudy, UCF Burnett College of Biomedical Sciences,
407-823-1206, pk@mail.ucf.edu
This
page is dedicated to
MCPIP | Heartdisease | Heartattack
The information
is derived from believed to be reliable - public domain sources
and is not
meant to be medical advice. |
MCPIP | Heartdisease |
Heartattack
|